Electronic Journal of Differential Equations, Vol. 2003(2003), No. 68, pp. 1-12. Title: Global solution for the Kadomtsev-Petviashvili equation (KPII) in anisotropic Sobolev spaces of negative indices Authors: Pedro Isaza J. (Univ. Nacional de Colombia, Medellin, Colombia) Jorge Mejia L. (Univ. Nacional de Colombia, Medellin, Colombia) Abstract: It is proved that the Cauchy problem for the Kadomtsev-Petviashvili equation (KPII) is globally well-posed for initial data in anisotropic Sobolev spaces $H^{s0}(\mathbb{R}^2)$ with $s>-1/14$. The extension of a local solution to a solution in an arbitrary interval is carried out by means of an almost conservation property of the $H^{s0}$ norm of the solution. Submitted September 13, 2002. Published June 13, 2003. Math Subject Classifications: 35Q53, 37K05. Key Words: Nonlinear dispersive equations; global solutions; almost conservation laws.