Electronic Journal of Differential Equations, Vol. 2007(2007), No. 150, pp. 1-9. Title: Global well-posedness for the 2D quasi-geostrophic equation in a critical Besov space Author: Atanas Stefanov (Univ. of Kansas, Lawrence, KS, USA) Abstract: We show that the 2D quasi-geostrophic equation has global and unique strong solution when the (large) data belongs in the critical scale invariant space $\dot{B}^{2-2\alpha}_{2, \infty}\cap L^{2/(2\alpha-1)}$. Submitted November 10, 2006. Published November 09, 2007. Math Subject Classifications: 35Q35, 36D03, 35K55, 76B65 Key Words: 2D quasi-geostrophic equations.