Electronic Journal of Differential Equations, Vol. 2008(2008), No. 87, pp. 1-10. Title: Positive solutions to nonlinear second-order three-point boundary-value problems for difference equation with change of sign Authors: Chunli Wang (Univ. of Electronic Technology, Guilin, Guangxi, China) Xiaoshuang Han (Yanbian Univ. Yanji, Jilin, China) Chunhong Li (Yanbian Univ. Yanji, Jilin, China) Abstract: In this paper we investigate the existence of positive solution to the discrete second-order three-point boundary-value problem $$\displaylines{ \Delta^2 x_{k-1}+ h(k) f(x_k)=0, \quad k \in [1, n], \cr x_0 =0, \quad a x_l = x_{n+1}, }$$ where $n \in [2, \infty)$, $l \in [1, n]$, $0 < a < 1$, $(1-a)l \geq 2$, $(1+a)l\leq n+1$, $f \in C(\mathbb{R}^+,\mathbb{R}^+)$ and $h(t)$ is a function that may change sign on $[1, n]$. Using the fixed-point index theory, we prove the existence of positive solution for the above boundary-value problem. Submitted March 6, 2008. Published June 11, 2008. Math Subject Classifications: 39A05, 39A10. Key Words: Boundary value problem; positive solution; difference equation; fixed point; changing sign coefficients.