Electronic Journal of Differential Equations, Vol. 2009(2009), No. 116, pp. 1-43. Title: Sufficient conditions of local solvability for partial differential operators on spaces of Colombeau type Author: Claudia Garetto (Leopold-Franzens Univ., Innsbruck, Austria) Abstract: We provide sufficient conditions of local solvability for partial differential operators with variable Colombeau coefficients. We mainly concentrate on operators which admit a right generalized pseudodifferential parametrix and on operators which are a bounded perturbation of a differential operator with constant Colombeau coefficients. The local solutions are intended in the Colombeau algebra $\mathcal{G}(\Omega)$ as well as in the dual $\mathcal{L}(\mathcal{G}_c(\Omega),\widetilde{\mathbb{C}})$. Submitted June 22, 2009. Published September 21, 2009. Math Subject Classifications: 46F30, 35D99. Key Words: Algebras of generalized functions; generalized solutions of partial differential equations.