Electronic Journal of Differential Equations, Vol. 2009(2009), No. 96, pp. 1-10. Title: Existence of solutions for an abstract second-order differential equation with nonlocal conditions Author: Eduardo Hernandez (Univ.de Sao Paulo, Brazil) Abstract: We discuss the existence of mild solutions for abstract second-order differential equation with nonlocal conditions. Also we consider some application of our results. Submitted December 2, 2008. Published August 11, 2009. Math Subject Classifications: 35R10, 47D09. Key Words: Second order differential equations; cosine function of operators; abstract Cauchy problem.