Electronic Journal of Differential Equations, Vol. 2010(2010), No. 105, pp. 1-5. Title: Regularity of generalized Naveir-Stokes equations in terms of direction of the velocity Author: Yuwen Luo (Chongqing Univ. of Technology, China) Abstract: In this article, the author studies the regularity of 3D generalized Navier-Stokes (GNS) equations with fractional dissipative terms $(-\Delta)^{\alpha} u$. It is proved that if $\hbox{div} (u / |u|) \in L^p (0, T ; L^q (\mathbb{R}^3))$ with $$ \frac{2 \alpha}{p} + \frac{3}{q} \leq 2 \alpha - \frac{3}{2},\quad \frac{6}{4 \alpha-3} < q \leq \infty . $$ then any smooth on GNS in $[0,T)$ remains smooth on $[0, T]$. Submitted April 8, 2010. Published August 02, 2010. Math Subject Classifications: 35D10, 35Q35, 76D03. Key Words: Generalized Navier-Stokes equation; regularity; Serrin criteria.