Electronic Journal of Differential Equations, Vol. 2012 (2012), No. 199, pp. 1-13. Title: Necessary and sufficient conditions for the existence of periodic solutions in a predator-prey model on time scales Authors: Xingyong Liu (South China Normal Univ., Guangzhou, China) Xiuxiang Liu (South China Normal Univ., Guangzhou, China) Abstract: This article explores the existence of periodic solutions for non-autonomous impulsive semi-ratio-dependent predator-prey systems on time scales. Based on a continuous theorem in coincidence degree theory, sharp sufficient and necessary conditions are derived in which most popular monotonic, non-monotonic and predator functional responses are applicable. This article extends the work in [6,10,12,13,134,18,25]. Submitted July 16, 2012. Published November 15, 2012. Math Subject Classifications: 34A34, 34C25, 92D25. Key Words: Time scales; periodic solutions; predator-prey system; functional responses.