Electronic Journal of Differential Equations, Vol. 2012 (2012), No. 74, pp. 1-15. Title: Initial-value problems for first-order differential systems with general nonlocal conditions Author: Octavia Nica (Babes-Bolyai Univ., Cluj, Romania) Abstract: This article concerns the existence of solutions to initial-value problems for nonlinear first-order differential systems with nonlocal conditions of functional type. The fixed point principles by Perov, Schauder and Leray-Schauder are applied to a nonlinear integral operator split into two operators, one of Fredholm type and the other of Volterra type. The novelty in this article is combining this approach with the technique that uses convergent to zero matrices and vector norms. Submitted February 17, 2012. Published May 14, 2012. Math Subject Classifications: 34A34, 34A12, 45G10 Key Words: Nonlinear differential system; nonlocal initial condition; fixed point; vector norm; matrix convergent to zero.