Electronic Journal of Differential Equations, Vol. 2013 (2013), No. 231, pp. 1-10. Title: Selfadjoint extensions of multipoint singular differential operators Author: Zameddin I. Ismailov (Karadeniz Technical Univ., Trabzon, Turkey) Abstract: This article describes all selfadjoint extensions of the minimal operator generated by a linear singular multipoint symmetric differential-operator expression for first order in the direct sum of Hilbert spaces of vector-functions. This description is done in terms of the boundary values, and it uses the Everitt-Zettl and the Calkin-Gorbachuk methods. Also the structure of the spectrum of these extensions is studied. Submitted September 19, 2013. Published October 18, 2013. Math Subject Classifications: 47A10. Key Words: Everitt-Zettl and Calkin-Gorbachuk methods; singular multipoint; differential operators; selfadjoint extension; spectrum