Nicoleta E. Tarfulea
Abstract:
We study the effectiveness of drug therapy for an HIV infection age
mathematical model that considers both virus-to-cell and cell-to-cell
infections, as well as the immune response. As expected, in the presence of
perfect inhibitors, the populations of infected cells, virus, and effector
cells decay exponentially to zero. When protease inhibitors are used, the
production of infectious virions is diminished, as demonstrated in our drug
therapy model.
Published August 20, 2024.
Math Subject Classifications: 34K12, 92D30, 92C50.
Key Words: HIV infection; viral age model; drug therapy; inhibitors.
DOI: 10.58997/ejde.conf.27.t1
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Nicoleta E. Tarfulea Department of Mathematics and Statistics Purdue University Northwest Indiana 46323, USA email: netarful@purdue.edu |
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